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Antibody Product Overview
| ELK.No | EM1275 |
| Product name | Cystatin C (7F11) Mouse mAb |
| Reactivity | Human |
| Applications | WB, IHC, ELISA |
| Other name | AD8, Cystatin3, Gamma trace, HCCAA |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 1471 |
| Human Swiss-Prot | P01034 |
| Source | Mouse |
| Isotype | IgG1 |
| Target | |
| Fields | |
| Gene name | |
| Protein name | |
| Human gene link | |
| Human Swiss link | |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Recombinant Protein |
| Specificity | |
| Formulation | |
| Clonality | Monoclonal |
| Dilution | WB 1:1,000-2,000 IHC 1:100-200 ELISA 1:10,000-20,000 |
| Purification | |
| Concentration | 1mg/mL |
| Storage stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Molecular Weight (Da) | |
| Observed band (KD) | 14kDa |
| Background | Cystatin C is a 13-kDa inhibitor of cysteine proteinases which is secreted by all cell types and is completely cleared from the organism through glomerular filtration, shown to be an early and sensitive biomarker of renal dysfunction. A mutation in Cystatin C has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. In addition, this protein has been shown to have an antimicrobial function, inhibiting the replication of herpes simplex virus. |
| Function | |
| Subcellular location | Secreted |
| Expression |
Additional Images
Immunohistochemical analysis of paraffin-embedded Human Kidney Tissue using Cystatin C（EM1275）Mouse mAb diluted at 1:200.
Immunohistochemical analysis of paraffin-embedded Human Brain Tissue using Cystatin C（EM1275）Mouse mAb diluted at 1:200.
: EM1275-100
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