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Antibody Product Overview
| ELK.No | EM1404 |
| Product name | P63-α (3F11) Mouse mAb |
| Reactivity | Human, Rat, Mouse |
| Applications | WB, IHC |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 8626 |
| Human Swiss-Prot | Q9H3D4 |
| Source | Mouse |
| Isotype | IgG1 |
| Target | |
| Fields | |
| Gene name | |
| Protein name | |
| Human gene link | |
| Human Swiss link | |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthetic Peptide |
| Specificity | |
| Formulation | |
| Clonality | Monoclonal |
| Dilution | WB 1:1,000-2,000 IHC:1;100-1:200 |
| Purification | |
| Concentration | 1mg/mL |
| Storage stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Molecular Weight (Da) | |
| Observed band (KD) | 50-80kDa |
| Background | p63 can induce p53-responsive genes and apoptosis, mutation of p63 rarely results in tumors . Research investigators frequently observe amplification of the p63 gene in squamous cell carcinomas of the lung, head and neck . The p63 gene contains an alternative transcription initiation site that yields a 40 kDa δNp63 lacking the transactivation domain, and alternative splicing at the carboxy-terminus yields the α, β, and γ isoforms . |
| Function | |
| Subcellular location | Nucleus |
| Expression |
Additional Images
Western blot analysis of 1) A431 Cell Lysate, 2) 3T3 Cell Lysate , 3) PC-12 Cell Lysate using P63-α（EM1404）Mouse mAb diluted at 1:2000.
Immunohistochemical analysis of paraffin-embedded Human Prostate Tissue using P63-α（EM1404）Mouse mAb diluted at 1:200.
Immunohistochemical analysis of paraffin-embedded Human Prostate Tissue using P63-α（EM1404）Mouse mAb diluted at 1:200.
: EM1404-100
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