Anti-Axin 1 Rabbit pAb, Primary Antibody
Ref: AO-03-GB11729
Volume: 10, 25, 50 and 100 µl
Product Information
|
Description |
Axin 1 rabbit polyclonal antibody |
|
Protein full name |
Axin-1 |
|
Synonyms |
Axin1, AXIN1, AXIN, PPP1R49, Axin 1, Axis inhibition protein 1, Axis Inhibitor 1, Protein phosphatase 1 regulatory subunit 49, Protein Fused, PPP1R49 |
|
Immunogen |
Recombinant protein corresponding to Human Axin 1 |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Predicted MW. |
96 kDa |
|
Observed MW. |
110 kDa |
|
Uniprot ID |
O15169, O35625, O70239 |
Applications
|
Applications |
Species |
Dilution |
Positive Tissue |
|
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
lung |
Background
Axin-1 encoded by the AXIN1 gene in human is a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. This protein interacts with adenomatosis polyposis coli, catenin (cadherin-associated protein) beta 1, glycogen synthase kinase 3 beta, protein phosphatase 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medulloblastomas.
Images
 |
Western blot analysis of Axin1 (GB11729) at dilution of 1: 500 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
For Research Use Only!
For Research Use Only!
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