Anti-Fas Ligand Rabbit pAb, Primary Antibody

Anti-Fas Ligand Rabbit pAb, Primary Antibody

AO-03-GB11090-1-50

Anti-Fas Ligand  Rabbit pAb, Primary Antibody

Volume : 50 µL
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€299.00
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Anti-Fas Ligand Rabbit pAb

Description

Fas Ligand rabbit polyclonal antibody

Protein full name

Tumor necrosis factor receptor superfamily member 6

Synonyms

ALPS1A, APO 1, Apo 1 antigen, APT1, CD95, FAS, FAS1, FASLG receptor, FASTM, TNFRSF6

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse FASL

Isotype

IgG

Purity

Affinity purification

Subcellular location

Membrane

Uniprot ID

P48023, P41047, P36940


Applications

Applications

Species

Dilution

Positive Sample

IHC/IF

Human, Mouse, Rat

1: 500-1: 3000

epityphlon, spleen, thymus


Background

Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.


Images

Picture 1.png

Immunohistochemistry of paraffin embedded human epityphlon using FasL (GB11090-1) at dilution of 1:1500 (400x lens)
Picture 2.png Immunohistochemistry of paraffin embedded mouse spleen using FasL (GB11090-1) at dilution of 1:1500 (400x lens)
Picture 3.png Immunohistochemistry of paraffin embedded rat spleen using FasL (GB11090-1) at dilution of 1:1500 (400x lens)
Picture 4.png Immunofluorescence of paraffin embedded rat spleen using FasL (GB11090-1) at dilution of 1:1500 (400x lens)
Picture 5.png Immunofluorescence of paraffin embedded rat thymus using FasL (GB11090-1) at dilution of 1:1500 (400x lens)


Storage

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

: AO-03-GB11090-1-50
: 10 Items
Hurry! only 10 items left in stock.

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