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Anti-FAK Rabbit pAb, Primary Antibody
AO-03-GB11545
Product Information
|
Description |
FAK rabbit polyclonal antibody |
|
Protein full name |
Focal adhesion kinase 1 |
|
Synonyms |
PTK2, FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK, protein tyrosine kinase 2 |
|
Immunogen |
Recombinant protein corresponding to Mouse FAK |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Nucleus, Plasma membrane, Cytoskeleton |
|
Uniprot ID |
Q05397, P34152, O35346 |
Applications
|
Applications |
Species |
Dilution |
Positive Sample |
|
IHC/IF |
Human, Mouse, Rat |
1:1000-1:2000 |
brain, breast cancer, heart, kidney |
Background
FAK is a protein of 125 kD recruited as a participant in focal adhesion dynamics between cells, and has a role in motility and cell survival. FAK is a highly conserved, non-receptor tyrosine kinase originally identified as a substrate for the oncogene protein tyrosine kinase v-src. This cytosolic kinase has been implicated in diverse cellular roles including cell locomotion, mitogen response and cell survival.
Images
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Immunohistochemistry of paraffin embedded human breast cancer using FAK (GB11545) at dilution of 1:1000 (400x lens) |
 |
Immunohistochemistry of paraffin embedded human kidney using FAK (GB11545) at dilution of 1:1000 (400x lens) |
 |
Immunohistochemistry of paraffin embedded mouse brain using FAK (GB11545) at dilution of 1:1000 (400x lens) |
 |
Immunohistochemistry of paraffin embedded rat brain using FAK (GB11545) at dilution of 1:1000 (400x lens) |
 |
Immunofluorescence of paraffin embedded mouse brain using FAK (GB11545) at dilution of 1:1000 (400x lens) |
 |
Immunofluorescence of paraffin embedded rat heart using FAK (GB11545) at dilution of 1:1000 (400x lens) |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
: AO-03-GB11545
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