Product Information
|
Protein full name |
Regulation of nuclear pre-mRNA domain-containing protein 1A |
|
Synonyms |
HsT3101, p15INK4B related protein, P15RS, RPRD1A |
|
Uniprot ID |
Q8VDS4 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse P15RS |
|
Isotype |
IgG |
|
Predicted MW./Observed MW. |
36 kDa / 36 kDa |
|
Purity |
Affinity purification |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse | 1: 700-1: 1500 | brain |
Background
Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. May act as a negative regulator of cyclin-D1 (CCND1) and cyclin-E (CCNE1) in the cell cycle.
Images
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|
WB analysis of P15RS(GB115338). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Primary antibody: 1: 1500, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h. |
Storage
| Storage | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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