Anti-CDK5RAP1 Rabbit pAb

Anti-CDK5RAP1 Rabbit pAb

Antibodies Oncology
AO-03-GB113634-50
113634,C42,RP5-1187J4.1,GB113634,CGI 05,CDK5 activator-binding protein C42,CDK5 regulatory subunit-associated protein 1,CDK5RAP1,HSPC167,CDK 5RAP 1,CDK5RAP1.3,CDK5RAP1.4,CDK-5RAP-1,C20orf34,Mitochondrial tRNA methylthiotransferase CDK5RAP1
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Product Information


Protein full name

Mitochondrial tRNA methylthiotransferase CDK5RAP1

Synonyms

C20orf34, C42, CDK5RAP1, CDK5RAP1.3, CDK5RAP1.4, CGI 05, HSPC167, CDK5 activator-binding protein C42, CDK5 regulatory subunit-associated protein 1, RP5-1187J4.1

Uniprot ID

Q8BTW8

Immunogen

Recombinant protein corresponding to Mouse CDK5RAP1

Isotype

IgG

Predicted MW./Observed MW.

66 kDa / 72 kDa

Purity

Affinity purification



Applications


Applications Species Dilution Positive Tissue
WB Human, Rat 1: 500-1: 800 HeLa, C6, A549



Background

Cyclin dependent kinase 5 (Cdk5) is a key regulator of cell cycle progression in neuronal differentiation that physically associates with and is activated by the neuron-specific protein p35. CDK5RAP1 (Cdk5 regulatory subunit-associated protein 1), also known as Cdk5 activator-binding protein C42, is a 601 amino acid protein that specifically inhibits Cdk5 activation by p35 through formation of a dimer that inhibits kinase activity.



Images

018cP0H67loza8B.jpg

 WB analysis of CDK5RAP1(GB113634).
Sample: Protein treated by RIPA Lysis Buffer (G2002).
Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h.
Primary antibody: 1: 800, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.



Storage


Storage Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.


: AO-03-GB113634-50
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Hurry! only 10 items left in stock.

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