Anti-CDKA1/DOC1 Rabbit pAb
   

Anti-CDKA1/DOC1 Rabbit pAb

Antibodies Oncology
AO-03-GB113222-50
DOC-1,CDK2-associated protein 1,GB113222,CDKA-1,Putative oral cancer suppressor,Cdkap1,DORC1,p12DOC 1,DOC 1,Cdk2ap1,CDKA1 / DOC1,ST19,Deleted in oral cancer 1,113222,Doc1,CDKA 1,Cyclin-dependent kinase 2-associated protein 1
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Product Information


Protein full name

Cyclin-dependent kinase 2-associated protein 1

Synonyms

CDK2-associated protein 1, Deleted in oral cancer 1, DOC-1, Putative oral cancer suppressor, Cdk2ap1, Cdkap1, Doc1, p12DOC 1, ST19, DORC1

Uniprot ID

O35207

Immunogen

Recombinant protein corresponding to Mouse CDKA1 / DOC1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus, Cytoplasm



Applications


Applications Species Dilution Positive Tissue
IHC/IF Human, Mouse, Rat 1: 600-1: 1200 colon, stomach, kidney



Background

The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle.



Images

013VthsxbnfOAeY.jpg

 IHC analysis of CDKA1/DOC1(GB113222).
Sample: Human colon, 4% PFA (G1101) 12-24h.
Antigen retrieval: Citrate buffer (pH 6.0) (G1201), 98℃, 20 min.
Primary antibody: 1: 1200, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.

02TXNsziyZEnP5L.jpg

 IHC analysis of CDKA1/DOC1(GB113222).
Sample: Mouse colon, 4% PFA (G1101) 12-24h.
Antigen retrieval: Citrate buffer (pH 6.0) (G1201), 98℃, 20 min.
Primary antibody: 1: 1200, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.

039SVEuCXCLMsFu.jpg

 IHC analysis of CDKA1/DOC1(GB113222).
Sample: Rat colon, 4% PFA (G1101) 12-24h.
Antigen retrieval: Citrate buffer (pH 6.0) (G1201), 98℃, 20 min.
Primary antibody: 1: 1200, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.

04nf8TaQFt9YXD3.jpg

 IHC analysis of CDKA1/DOC1(GB113222).
Sample: Human stomch, 4% PFA (G1101) 12-24h.
Antigen retrieval: Citrate buffer (pH 6.0) (G1201), 98℃, 20 min.
Primary antibody: 1: 1200, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.

05Qqjp76i7EmoTZ.jpg

 IHC analysis of CDKA1/DOC1(GB113222).
Sample: Mouse kidney, 4% PFA (G1101) 12-24h.
Antigen retrieval: Citrate buffer (pH 6.0) (G1201), 98℃, 20 min.
Primary antibody: 1: 1200, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.



Storage


Storage Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.


: AO-03-GB113222-50
: 10 Items
Hurry! only 10 items left in stock.

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