Anti-Tal1 Rabbit pAb

Anti-Tal1 Rabbit pAb

Antibodies Oncology
AO-03-GB11885-50
SCL,T-cell acute lymphocytic leukemia 1,11885,GB11885,GB11885100,Tal-1,erythroid differentiation factor,Tal1,tal-1,TAL bHLH transcription factor 1,TAL1,TCL5,Tal 1,bHLHa17,T-cell acute lymphocytic leukemia protein 1 homolog
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Product Information


Protein full name

T-cell acute lymphocytic leukemia protein 1 homolog

Synonyms

Tal1, TAL1, SCL, TCL5, bHLHa17, tal-1, T-cell acute lymphocytic leukemia 1, TAL bHLH transcription factor 1, erythroid differentiation factor

Uniprot ID

P22091

Immunogen

Recombinant protein corresponding to Mouse Tal1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus



Applications


Applications Species Dilution Positive Tissue
IHC/IF Rat 1: 400-1: 1500 hepatitis, pneumonia



Background

Activation of TAL1 characterizes up to 60% of cases of human T cell acute lymphoblastic leukemia, making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box.



Images

01EO9kngTtifTPV.jpg

 IHC analysis of Tal1(GB11885).
Sample: Rat hepatitis, 4% PFA (G1101) 12-24h.
Antigen retrieval: Citrate buffer (pH 6.0) (G1201), 98℃, 20 min.
Primary antibody: 1: 1500, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.

02ljTqiwiUNWbKA.jpg

 IHC analysis of Tal1(GB11885).
Sample: Rat pneumonia, 4% PFA (G1101) 12-24h.
Antigen retrieval: Citrate buffer (pH 6.0) (G1201), 98℃, 20 min.
Primary antibody: 1: 1500, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.



Storage


Storage Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.


: AO-03-GB11885-50
: 10 Items
Hurry! only 10 items left in stock.

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