Product Information
|
Protein full name |
Cyclin-D1-binding protein 1 |
|
Synonyms |
CCNDBP1, Cyclin D1 binding protein 1, DIP1, GCIP, HHM, Human homolog of Maid |
|
Uniprot ID |
Q3TVC7 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse CCNDBP1 |
|
Isotype |
IgG |
|
Predicted MW./Observed MW. |
39 kDa / 40 kDa |
|
Purity |
Affinity purification |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat | 1: 800-1: 1200 | liver |
Background
May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription . May be required for hepatocyte proliferation.
Images
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WB analysis of CCNDBP1(GB114679). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Primary antibody: 1: 1200, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h. |
|
|
WB analysis of CCNDBP1(GB114679). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Primary antibody: 1: 1200, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h. |
Storage
| Storage | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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