Anti-Cyclin D3/CCND3 Rabbit pAb

Anti-Cyclin D3/CCND3 Rabbit pAb

Antibodies Oncology
AO-03-GB111250-100
Ccnd3,D-3,Cyclin D3/CCND3,D3 type cyclin,CyclinD3,GB111250,CD 3,GB111250100,CD-3,Cyclin-D3,G1 S specific cyclin D3,111250,CCND-3,D 3,CD3,Cyl-3,CCND 3,G1/S-specific cyclin-D3
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Product Information


Protein full name

G1/S-specific cyclin-D3

Synonyms

Ccnd3, Cyl-3, CyclinD3, D3 type cyclin, G1 S specific cyclin D3

Uniprot ID

P30282

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Cyclin D3

Isotype

IgG

Predicted MW./Observed MW.

32 kDa / 32 kDa

Purity

Affinity purification



Applications


Applications Species Dilution Positive Tissue
WB Human, Mouse, Rat 1: 500-1: 1000 liver, kidney



Background

Cyclin D3 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition.



Images

01NqUAtxLEw91qx.jpg

 WB analysis of Cyclin D3/CCND3(GB111250).
Sample: Protein treated by RIPA Lysis Buffer (G2002).
Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h.
Primary antibody: 1: 500, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.



Storage


Storage Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.


: AO-03-GB111250-100
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