Anti-p18 INK4c Rabbit pAb

Anti-p18 INK4c Rabbit pAb

Antibodies Oncology
AO-03-GB11810-100
p18INK4c,p18-INK4C,pI,INK 4,INK4C,p 18,GB11810,GB11810100,cyc,p18-INK4c,CDKN2C,p18,p18 INK4c,INK-4c,p-18,11810,INK-4,cyclin-dependent kinase inhibitor 2C,Cdkn2c,INK 4c,Cyclin-dependent kinase 4 inhibitor C
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Product Information


Protein full name

Cyclin-dependent kinase 4 inhibitor C

Synonyms

Cdkn2c, CDKN2C, INK4C, p18, p18-INK4C, cyclin-dependent kinase inhibitor 2C, cyclin dependent kinase inhibitor 2C

Uniprot ID

Q60772

Immunogen

Recombinant protein corresponding to Mouse CDKN2C

Isotype

IgG

Predicted MW./Observed MW.

18 kDa / 18 kDa

Purity

Affinity purification



Applications


Applications Species Dilution Positive Tissue
WB Mouse, Rat 1: 500-1: 1000 kidney, brain



Background

Cyclin-dependent kinase 4 inhibitor C is an enzyme encoded by the CDKN2C gene. The protein is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function.



Images

01SGO6Tp0fj9vWx.jpg

 WB analysis of p18 INK4c(GB11810).
Sample: Protein treated by RIPA Lysis Buffer (G2002).
Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h.
Primary antibody: 1: 500, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.



Storage


Storage Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.


: AO-03-GB11810-100
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