Product Information
|
Protein full name |
T-cell surface glycoprotein CD8 alpha chain |
|
Synonyms |
T-lymphocyte differentiation antigen T8/Leu-2, CD8a, MAL, Leu2, Leu2 T lymphocyte antigen, Ly 35, LYT3, p32, T8 T cell antigen, CD8A, CD8, Leu2, p32, CD8a molecule, CD8 alpha |
|
Uniprot ID |
P01731 |
|
Immunogen |
Recombinant protein corresponding to Mouse CD8 alpha |
|
Predicted MW./Observed MW. |
27 kDa / 33-37 kDa |
|
Purity |
Affinity purification |
|
conjugation |
HRP |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Mouse | 1: 500-1: 1000 | thymus, lymph node |
Background
Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs).
Images
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WB analysis of CD8 alpha(ZB114196-HRP). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Antibody: HRP conjugated anti-CD8 alpha antibody 1: 500, 4℃ overnight. |
Storage
| Storage | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
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