Product Information | |||||
Protein full name | 5'-nucleotidase | ||||
Synonyms | 5 NT, 5 nucleotidase, 5' nucleotidase, ecto (CD73), CD73, E5NT, Ecto 5 nucleotidase, eN, eNT, NT, NT5, NT5E,5'-NT, Nt5e, Nt5, Nte | ||||
Immunogen | Recombinant protein corresponding to Mouse CD73 | ||||
Uniprot ID | Q61503 | ||||
Isotype | IgG | ||||
Conjugation | FITC | ||||
Purity | Affinity purification | ||||
Subcellular location | Cell membrane | ||||
Predicted MW. / Observed MW. | 64 kDa / 64-70 kDa | ||||
Applications | Species | Dilution | Positive Tissue | ||
FC | Human, Mouse, Rat | 1: 100-1: 200 | R-MSC, 4T1 | ||
Storage | |||||
Storage | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. | ||||
Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. | ||||
background | |||||
CD73 is a glycosyl-phosphatidylinositol (GPI)-anchored adhesion protein that catalyzes the dephosphorylation of extracellular purine and pyrimidine nucleotides to their corresponding bioactive nucleosides. CD73 is a dimer of two identical subunits that depends on GPI to link with the external face of the plasma membrane. Similar to other GPI-anchored proteins, CD73 mediates co-stimulatory signals in T cell activation. CD73 has few structural variants, yet elicits diverse biological function through differential regulation in endothelial cells (EC), subpopulations of B and T cells, germinal center follicular dendritic cells and on thymic medullary reticular fibroblasts. | |||||
Images | |||||
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Flow cytometric analysis of CD73.Sample: R-MSC. | Flow cytometric analysis of CD73.Sample: 4T1.Antibody: FITC conjugated Anti-CD73 Rabbit pAb(ZB115637-FITC red histogram), 1: 100, RT 30 min. | ||||
For Research Use Only! Ver. No.: V3.1-20250918
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