Anti-Kindlin-1 Rabbit pAb

Anti-Kindlin-1 Rabbit pAb

Antibodies-Oncology
AO-03-GB114813-100
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Product Information


Protein full name

Fermitin family homolog 1

Synonyms

C20orf42, DTGCU2, Fermitin family homolog 1, FERMT1, KIND1, Kindlerin, Kindlin 1, Kindlin syndrome protein

Uniprot ID

P59113

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Kindlin-1

Isotype

IgG

Predicted MW./Observed MW.

77 kDa / 75 kDa

Purity

Affinity purification



Applications


Applications Species Dilution Positive Tissue
WB Human 1: 2000-1: 3000 HCT 116, HT-29, 293



Background

Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites.



Images

01KeeQuUlKaVl4e.jpg

 WB analysis of Kindlin-1(GB114813).
Sample: Protein treated by RIPA Lysis Buffer (G2002).
Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h.
Primary antibody: 1: 2000, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.



Storage


Storage Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.


Antibodies-Oncology
: AO-03-GB114813-100
: 10 Items
Hurry! only 10 items left in stock.

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