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Product Information
|
Protein full name |
NUT family member 1 |
|
Synonyms |
Nuclear protein in testis, Nutm1, Nut, C15orf55, Chromosome 15 open reading frame 55 |
|
Uniprot ID |
Q8BHP2 |
|
Immunogen |
Recombinant protein corresponding to Mouse NUT |
|
Isotype |
IgG |
|
Predicted MW./Observed MW. |
121 kDa / 121 kDa |
|
Purity |
Affinity purification |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Rat | 1: 1000-1: 2000 | heart |
Background
Nuclear protein in testis is a 1,132 amino acid protein that is specifically expressed in testis. Belonging to the FAM22 family, NUT shuttles between nucleus and cytoplasm via a leptomycin-sensitive pathway. It is suggested that the translocation of the NUT gene is the cause of nuclear protein in testis midline carcinomas (NMC). NMCs are highly aggressive carcinomas typically arising in midline structures in young individuals.
Images
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WB analysis of NUT(GB1141). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Primary antibody: 1: 1000, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h. |
Storage
| Storage | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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