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Product Information
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Protein full name |
Dickkopf-related protein 1 |
|
Synonyms |
Dickkopf-1, Dkk-1, mDkk-1, Dkk1, SK, Dickkopf homolog 1 |
|
Uniprot ID |
O54908 |
|
Immunogen |
Recombinant protein corresponding to Mouse DKK1/KLH conjugated Synthetic peptide corresponding to Mouse DKK1 |
|
Isotype |
IgG |
|
Predicted MW./Observed MW. |
29 kDa / 34 kDa |
|
Purity |
Affinity purification |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat | 1: 300-1: 800 | HeLa, HepG2, Caco2 |
Background
This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
Images
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WB analysis of DKK1(GB112495). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Primary antibody: 1: 300, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h. |
Storage
| Storage | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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