Anti-Crk p38 Rabbit pAb

Anti-Crk p38 Rabbit pAb

Antibodies-Oncology
AO-03-GB11645-100
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€429.00
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Product Information


Protein full name

Adapter molecule crk

Synonyms

CRK, Crk p38, CRK isoform 2, CrkII; CRKII; p38, Proto oncogene C crk, v crk sarcoma virus CT10 oncogene homolog, Adapter molecule crk, Avian sarcoma virus CT10

Uniprot ID

P46108

Immunogen

Recombinant protein corresponding to Human Adapter molecule crk

Isotype

IgG

Predicted MW./Observed MW.

34 kDa / 38 kDa

Purity

Affinity purification



Applications


Applications Species Dilution Positive Tissue
WB Human 1: 500-1: 1000 HepG2, A549, MCF7



Background

Adapter molecule crk also known as proto-oncogene c-Crk or p38 is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. This protein has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation.



Images

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 WB analysis of Crk p38(GB11645).
Sample: Protein treated by RIPA Lysis Buffer (G2002).
Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h.
Primary antibody: 1: 500, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.



Storage


Storage Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.


Antibodies-Oncology
: AO-03-GB11645-100
: 10 Items
Hurry! only 10 items left in stock.

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