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Product Information
Protein full name | Mucin-16 (MUC-16) (Ovarian cancer-related tumor marker CA125) (CA-125) (Ovarian carcinoma antigen CA125) |
Gene Id | 94025 |
Immunogen | Synthesized peptide derived from human CA 125 |
Uniprot ID | Q8WXI7 |
Source | Mouse/IgG1, Kappa |
Concentration | 1 mg/ml |
Purity | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. |
Applications
IHC/IF | Human | 1: 200-1: 500 | ovarian cancer |
Background
MUC16, also named as CA125, is thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. It is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller “subunits” being described by some investigators. The antibody recognizes the C-term of MUC16.
Images
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Immunohistochemistry analysis of paraffin embedded human ovarian cancer using CA125 (GB14012) at dilution of 1: 200 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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