Anti-Phospho-PTEN(S380) Rabbit pAb

Anti-Phospho-PTEN(S380) Rabbit pAb

Antibodies-Oncology
AO-03-GB114583-50
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€299.00
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Product Information


Protein full name

Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

Synonyms

10q23del, Bannayan Zonana syndrome, BC005821, BZS, ITGA 2, MGC11227, MHAM, MMAC1, Multiple hamartoma (Cowden syndrome), phosphatase and tensin homolog, PTEN, PTEN1, TEP1, P-PETN

Uniprot ID

P60484

Immunogen

KLH conjugated Synthetic phosphopeptide corresponding to Human PTEN(S380)

Isotype

IgG

Predicted MW./Observed MW.

47/64/20 kDa / 54 kDa

Purity

Affinity purification



Applications


Applications Species Dilution Positive Tissue
WB Human, Mouse, Rat 1: 300-1: 600 HeLa, NIH/3T3, C6, 293



Background

PTEN(Phosphatase and tensin homolog) is also named as MMAC1, TEP1 and it modulates cell cycle progression and cell survival (blockage) through down-regulating the positive cell cycle-regulator (cycle D1) by its phosphatase activity and up-regulating the negative cell cycle regulator p21 (by its lipid phosphatase activity). PTEN is an important tumor suppressor whose inactivation frequency in cancers is ranked second after p53 tumor suppressor inactivation.



Images

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 WB analysis of Phospho-PTEN(S380)(GB114583).
Sample: Protein treated by RIPA Lysis Buffer (G2002).
Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h.
Primary antibody: 1: 300, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.



Storage


Storage Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.


Antibodies-Oncology
: AO-03-GB114583-50
: 10 Items
Hurry! only 10 items left in stock.

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