Anti-MCL1 Rabbit pAb

Anti-MCL1 Rabbit pAb

Antibodies Oncology
AO-03-GB115658-50
bcl2-L-3,MCL1S,MCL1L,Myeloid cell leukemia 1,mcl1/EAT,BCL2L3,GB115658,Mcl1,BCL2 family apoptosis regulator,MCL1,Mcl-1,115658,MCL1-ES,TM,EAT,Induced myeloid leukemia cell differentiation protein Mcl-1 homolog
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Product Information


Protein full name

Induced myeloid leukemia cell differentiation protein Mcl-1 homolog

Synonyms

Mcl1, MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT, Myeloid cell leukemia 1, BCL2 family apoptosis regulator, BCL2 family apoptosis regulator

Uniprot ID

P97287

Immunogen

Recombinant protein corresponding to Mouse MCL1

Isotype

IgG

Predicted MW./Observed MW.

35 kDa / 35 kDa

Purity

Affinity purification



Applications


Applications Species Dilution Positive Tissue
WB Mouse, Rat 1: 500-1: 1000 A20, spleen, NIH/3T3



Background

Induced myeloid leukemia cell differentiation protein Mcl-1 belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing.



Images

01NREqhpc7AwSsH.jpg

 WB analysis of MCL1(GB115658).
Sample: Protein treated by RIPA Lysis Buffer (G2002).
Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h.
Primary antibody: 1: 500, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.



Storage


Storage Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.


: AO-03-GB115658-50
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