Anti-Bag1 Rabbit pAb

Anti-Bag1 Rabbit pAb

Antibodies Oncology
AO-03-GB115597-100
BAG1S,Bag-1,BAG1,RAP46,Bag 1,BAG1L speicfic,BAG1M,HAP,BAG 1,115597,GB115597100,GB115597,BAG family molecular chaperone regulator 1
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Product Information


Protein full name

BAG family molecular chaperone regulator 1

Synonyms

BAG 1, BAG1, BAG1L speicfic, BAG1M, BAG1S, HAP, RAP46

Uniprot ID

Q60739

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Bag1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus, Cytoplasm



Applications


Applications Species Dilution Positive Tissue
IHC/IF Mouse, Rat 1: 150-1: 600 testis



Background

Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain of HSPA8/HSC70. Inhibits the pro-apoptotic function of PPP1R15A, and has anti-apoptotic activity. Markedly increases the anti-cell death function of BCL2 induced by various stimuli.



Images

01jpqY5JFIzddZE.jpg

 IHC analysis of Bag1(GB115597).
Sample: Mouse testis, 4% PFA (G1101) 12-24h.
Antigen retrieval: Tris-EDTA buffer (pH 9.0) (G1203), 98℃, 20min.
Primary antibody: 1: 150, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.

02y7mPTRoE5dCih.jpg

 IHC analysis of Bag1(GB115597).
Sample: Rat testis, 4% PFA (G1101) 12-24h.
Antigen retrieval: Tris-EDTA buffer (pH 9.0) (G1203), 98℃, 20min.
Primary antibody: 1: 150, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.



Storage


Storage Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.


: AO-03-GB115597-100
: 10 Items
Hurry! only 10 items left in stock.

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