Anti-ALIX Rabbit pAb

Anti-ALIX Rabbit pAb

Antibodies Oncology
AO-03-GB114080-50
GB114080,外泌体标志物,AIP1,外泌体标记物,PDCD6 interacting protein,PDCD6IP,Alix,HP95,DRIP4,外泌体marker,114080,ALG 2 interacting protein 1,KIAA1375,外泌体,ALIX,Programmed cell death 6-interacting protein
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Product Information


Protein full name

Programmed cell death 6-interacting protein

Synonyms

AIP1, ALG 2 interacting protein 1, Alix, DRIP4, HP95, KIAA1375, PDCD6 interacting protein, PDCD6IP

Uniprot ID

Q9WU78

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse ALIX

Isotype

IgG

Predicted MW./Observed MW.

96 kDa / 115 kDa

Purity

Affinity purification



Applications


Applications Species Dilution Positive Tissue
WB Human 1: 1000-1: 2000 HeLa, Jurkat, K562



Background

Multifunctional protein involved in endocytosis, multivesicular body biogenesis, membrane repair, cytokinesis, apoptosis and maintenance of tight junction integrity. Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes.



Images

01aB639xkEZVDas.jpg

 WB analysis of ALIX(GB114080).
Sample: Protein treated by RIPA Lysis Buffer (G2002).
Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h.
Primary antibody: 1: 1000, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.



Storage


Storage Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.


: AO-03-GB114080-50
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