Product Information
|
Protein full name |
p53 apoptosis effector related to PMP-22 |
|
Synonyms |
KCP-1, Keratinocyte associated protein 1, KRTCAP1, P53 induced protein PIGPC1, Perp, PERP TP53 apoptosis effector, TP53 apoptosis effector, THW, PIGPC1 |
|
Uniprot ID |
Q9JK95 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse PERP |
|
Isotype |
IgG |
|
Purity |
Affinity purification |
|
Subcellular location |
Cell junction, Cell membrane |
Applications
| Applications | Species | Dilution | Positive Tissue |
| IHC/IF | Human, Rat | 1: 1500-1: 3000 | skin |
Background
Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway.
Images
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IHC analysis of PERP(GB113922). Sample: Rat skin, 4% PFA (G1101) 12-24h. Antigen retrieval: Citrate buffer (pH 6.0) (G1201), 98℃, 20 min. Primary antibody: 1: 3000, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h. |
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IF analysis of PERP(GB113922)red. Sample: Human skin, 4% PFA (G1101) 12-24h. Antigen retrieval: Tris-EDTA buffer (pH 9.0) (G1203), 98℃, 20min. Blocking buffer: 3% BSA (GC305010) in PBS, RT, 30min. Primary antibody: 1: 1500, 4℃ overnight. Secondary antibody: Cy3 conjugated Goat Anti-Rabbit IgG (H+L) (GB21303), 1: 300, RT, 1h. |
Storage
| Storage | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
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