Anti-Bad Rabbit pAb

Anti-Bad Rabbit pAb

Antibodies Oncology
AO-03-GB113746-100
Bcl2 antagonist of cell death,BBC6,BBC2,GB113746100,113746,Bcl2-L-8,GB113746,Bcl-2-binding component 6,BAD,BCL2L8,Bcl-2-like protein 8,Bcl2-associated agonist of cell death
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Product Information


Protein full name

Bcl2-associated agonist of cell death

Synonyms

BAD, BBC2, BBC6, Bcl-2-binding component 6, Bcl-2-like protein 8, Bcl2-L-8, BCL2L8, Bcl2 antagonist of cell death, Bcl-XL/Bcl-2-Associated Death Promoter

Uniprot ID

Q92934

Immunogen

KLH conjugated Synthetic peptide corresponding to Human Bad

Isotype

IgG

Predicted MW./Observed MW.

23 kDa / 23-26 kDa

Purity

Affinity purification



Applications


ApplicationsSpeciesDilutionPositive Tissue
WBHuman, Mouse, Rat1: 500-1: 1000brain, glioma



Background


BAD, also named as BBC6 and BCL2L8, promotes cell death. It is successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. BAD can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. It appears to act as a link between growth factor receptor signaling and the apoptotic pathways.



Images

01qMgjXbcbKEnzN.jpg                        

WB analysis of Bad(GB113746).
Sample: Protein treated by RIPA Lysis Buffer (G2002).
Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h.
Primary antibody: 1: 1000, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.

02KXm3Fsl7WXmL1.jpg                        

WB analysis of Bad(GB113746).
Sample: Protein treated by RIPA Lysis Buffer (G2002).
Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h.
Primary antibody: 1: 1000, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.



Storage


Storage            Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer            PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.


: AO-03-GB113746-100
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