Anti-Bax Mouse mAb, Primary Antibody

Anti-Bax Mouse mAb, Primary Antibody

AO-03-GB12690

Anti-Bax Mouse mAb, Primary Antibody

Anti-Bax Mouse mAb.pdf

Volume : 10 µL
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Anti -Bax Mouse mAb

RefAO-03-GB12690

Volume: 10, 25, 50 and 100 µl

Protein full name

Apoptosis regulator BAX

Synonyms

BAX, BCL2L4, BCL2 associated X protein, BCL2 associated X, apoptosis regulator

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Bax

Uniprot ID

Q07813

Isotype

IgG1,κ

Purity

Affinity purification

Predicted MW. / Observed MW.

21 kDa / 21 kDa

Applications

Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

liver, lung, kidney


Background

Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein.

Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.


Images

Picture 1.png

Western blot analysis of Bax (AO-03-GB12690) at dilution of 1: 1000


Storage

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 

 

 

 

: AO-03-GB12690
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