Product Information
Protein full name | Serine/threonine-protein kinase TBK1 |
Synonyms | T2K, TANK-binding kinase 1, Tbk1, NF kappa B activating kinase, FLJ11330 |
Uniprot ID | Q9WUN2 |
Immunogen | Recombinant protein corresponding to Mouse NAK/TBK1 |
Isotype | IgG |
Predicted MW./Observed MW. | 83 kDa / 95 kDa |
Purity | Affinity purification |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Mouse, Rat | 1: 1000-1: 2000 | liver |
Background
TBK1, also named as tumor necrosis factor (TNF) receptor-associated factor NF-kB activator (TANK)-binding kinase 1 (TBK1), NF-kB-activating kinase (NAK), T2K, is a multimeric kinase that modulates inflammation and autophagy. It is a ubiquitously expressed serine-threonine kinase belonging to the 'noncanonical IkB kinases' (IKKs) recognized for its critical role in regulating type I IFN production . And TBK1 is an important player in yet another critical cellular function, autophagy. This antibody is specific for TBK1.
Images
| WB analysis of NAK/TBK1(GB112943). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Primary antibody: 1: 1000, 4°C overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h. |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 µg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
Datasheet: Download datasheet 1
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