Anti-Axin 1 Rabbit pAb, Primary Antibody

AO-03-GB11729-10

Anti-Axin 1 Rabbit pAb, Primary Antibody

Anti-Axin 1 Rabbit pAb.pdf

Volume : 10 µL
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Anti-Axin 1 Rabbit pAb

Ref: AO-03-GB11729

Volume: 10, 25, 50 and 100 µl

Product Information

Description

Axin 1 rabbit polyclonal antibody

Protein full name

Axin-1

Synonyms

Axin1, AXIN1, AXIN, PPP1R49, Axin 1, Axis inhibition protein 1, Axis Inhibitor 1, Protein phosphatase 1 regulatory subunit 49, Protein Fused, PPP1R49

Immunogen

Recombinant protein corresponding to Human Axin 1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

96 kDa

Observed MW.

110 kDa

Uniprot ID

O15169, O35625, O70239


Applications

Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

lung


Background

Axin-1 encoded by the AXIN1 gene in human is a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. This protein interacts with adenomatosis polyposis coli, catenin (cadherin-associated protein) beta 1, glycogen synthase kinase 3 beta, protein phosphatase 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medulloblastomas.


Images

Picture 1.png

Western blot analysis of Axin1 (GB11729) at dilution of 1: 500


Storage

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

For Research Use Only!

 

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