Anti-Axin 1 Rabbit pAb, Primary Antibody
Anti-Axin 1 Rabbit pAb, Primary Antibody
Anti-Axin 1 Rabbit pAb, Primary Antibody
Ref: AO-03-GB11729
Volume: 10, 25, 50 and 100 µl
Product Information
Description |
Axin 1 rabbit polyclonal antibody |
Protein full name |
Axin-1 |
Synonyms |
Axin1, AXIN1, AXIN, PPP1R49, Axin 1, Axis inhibition protein 1, Axis Inhibitor 1, Protein phosphatase 1 regulatory subunit 49, Protein Fused, PPP1R49 |
Immunogen |
Recombinant protein corresponding to Human Axin 1 |
Isotype |
IgG |
Purity |
Affinity purification |
Predicted MW. |
96 kDa |
Observed MW. |
110 kDa |
Uniprot ID |
O15169, O35625, O70239 |
Applications
Applications |
Species |
Dilution |
Positive Tissue |
WB |
Human, Mouse, Rat |
1: 500-1: 1000 |
lung |
Background
Axin-1 encoded by the AXIN1 gene in human is a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. This protein interacts with adenomatosis polyposis coli, catenin (cadherin-associated protein) beta 1, glycogen synthase kinase 3 beta, protein phosphatase 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medulloblastomas.
Images
Western blot analysis of Axin1 (GB11729) at dilution of 1: 500 |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
For Research Use Only!
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