Anti-Fas Ligand Rabbit pAb, Primary Antibody
Anti-Fas Ligand Rabbit pAb, Primary Antibody
Anti-Fas Ligand Rabbit pAb, Primary Antibody
Anti-Fas Ligand Rabbit pAb
Description |
Fas Ligand rabbit polyclonal antibody |
Protein full name |
Tumor necrosis factor receptor superfamily member 6 |
Synonyms |
ALPS1A, APO 1, Apo 1 antigen, APT1, CD95, FAS, FAS1, FASLG receptor, FASTM, TNFRSF6 |
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse FASL |
Isotype |
IgG |
Purity |
Affinity purification |
Subcellular location |
Membrane |
Uniprot ID |
P48023, P41047, P36940 |
Applications
Applications |
Species |
Dilution |
Positive Sample |
IHC/IF |
Human, Mouse, Rat |
1: 500-1: 3000 |
epityphlon, spleen, thymus |
Background
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.
Images
Immunohistochemistry of paraffin embedded human epityphlon using FasL (GB11090-1) at dilution of 1:1500 (400x lens) | |
Immunohistochemistry of paraffin embedded mouse spleen using FasL (GB11090-1) at dilution of 1:1500 (400x lens) | |
Immunohistochemistry of paraffin embedded rat spleen using FasL (GB11090-1) at dilution of 1:1500 (400x lens) | |
Immunofluorescence of paraffin embedded rat spleen using FasL (GB11090-1) at dilution of 1:1500 (400x lens) | |
Immunofluorescence of paraffin embedded rat thymus using FasL (GB11090-1) at dilution of 1:1500 (400x lens) |
Storage
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
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