Product Information
|
Protein full name |
Dynactin subunit 2 |
|
Synonyms |
p50 dynamitin, 50 kDa dynein-associated polypeptide, Dynactin complex 50 kDa subunit, DCTN-50, GMP23-48K, Dctn2 |
|
Uniprot ID |
Q99KJ8 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse p50 dynamitin |
|
Isotype |
IgG |
|
Predicted MW./Observed MW. |
44 kDa / 50 kDa |
|
Purity |
Affinity purification |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat | 1: 500-1: 1000 | spleen, brain, testis |
Background
The Dynamitin modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.
Images
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|
WB analysis of p50 dynamitin(GB111192). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Primary antibody: 1: 500, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h. |
Storage
| Storage | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
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