Product Information
|
Protein full name |
Cyclin-dependent kinase inhibitor 1C |
|
Synonyms |
BWCR, BWS, CDKN1C, KIP2, p57, p57Kip2, WBS, Cyclin-dependent kinase inhibitor p57 |
|
Uniprot ID |
P49919 |
|
Immunogen |
KLH conjugated Synthetic peptide corresponding to Mouse p57 Kip2 |
|
Isotype |
IgG |
|
Predicted MW./Observed MW. |
37 kDa / 55 kDa |
|
Purity |
Affinity purification |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Mouse, Rat | 1: 1000-1: 2000 | pancreas |
Background
CDKN1C, also named as p57KIP2 and KIP2, belongs to the CDI family. CDKN1C is a potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. It is a negative regulator of cell proliferation. CDKN1C may play a role in maintenance of the non-proliferative state throughout life.
Images
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WB analysis of p57 Kip2(GB113714). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Primary antibody: 1: 2000, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h. |
Storage
| Storage | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).
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