Anti-DMC1 Rabbit pAb

Anti-DMC1 Rabbit pAb

Antibodies Oncology
AO-03-GB113631-100
HsLim15,113631,LIM15,DMC-1,Disrupted meiotic cDNA 1 homolog,GB113631,DMC1H,DMC1,DMC1 dosage suppressor of mck1 homolog,GB113631100,DNA meiotic recombinase 1,DMC 1,Meiotic recombination protein DMC1/LIM15 homolog
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Product Information


Protein full name

Meiotic recombination protein DMC1/LIM15 homolog

Synonyms

DMC1, DMC1H, HsLim15, LIM15, DNA meiotic recombinase 1, DMC1 dosage suppressor of mck1 homolog, Disrupted meiotic cDNA 1 homolog

Uniprot ID

Q61880

Immunogen

Recombinant protein corresponding to Mouse DMC1

Isotype

IgG

Predicted MW./Observed MW.

38 kDa / 38 kDa

Purity

Affinity purification



Applications


Applications Species Dilution Positive Tissue
WB Mouse 1: 500-1: 1000 liver



Background

DNA repair proteins are necessary for the maintenance of chromosome integrity and are involved in the elimination of premutagenic lesions from DNA. The DNA repair proteins Rad51 and Rad52 are key components of the double-strand-break repair (DSBR) pathway. Rad51 is essential for mitotic and meiotic recombination, and its mutation in yeast and mammalian cells results in chromosome loss. Overexpression of Rad52 confers resistance to ionizing radiation and induces homologous intrachromosomal recombination.



Images

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 WB analysis of DMC1(GB113631).
Sample: Protein treated by RIPA Lysis Buffer (G2002).
Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h.
Primary antibody: 1: 1000, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.



Storage


Storage Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.


: AO-03-GB113631-100
: 10 Produits
Hurry! only 10 items left in stock.

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