Anti-BRSK1 Rabbit pAb

Anti-BRSK1 Rabbit pAb

Antibodies Oncology
AO-03-GB111548-100
BRSK 1,BRSK1,GB111548100,BR serine/threonine-protein kinase 1,Serine/threonine-protein kinase SAD-B,Anti-BRSK1 Rabbit pAb,Brsk1,Sadb,111548,Brain-specific serine/threonine-protein kinase 1,BRSK-1,GB111548,Gm1100,Serine/threonine-protein kinase BRSK1
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Ajouter souhaits

Product Information


Protein full name

Serine/threonine-protein kinase BRSK1

Synonyms

Brain-specific serine/threonine-protein kinase 1, BR serine/threonine-protein kinase 1, Serine/threonine-protein kinase SAD-B, Brsk1, Gm1100, Sadb

Uniprot ID

Q5RJI5

Immunogen

Recombinant protein corresponding to Mouse BRSK1

Isotype

IgG

Predicted MW./Observed MW.

85 kDa / 90 kDa

Purity

Affinity purification



Applications


Applications Species Dilution Positive Tissue
WB Mouse 1: 500-1: 1000 brain, cerebral cortex, cerebellum



Background

BRSK1 was initially identified as a mammalian homolog to the fission yeast S. pombe Cdr2, a mitosis-regulatory kinase and also shows significant homology to the C. elegans neuronal cell polarity regulator SAD1. Similar to its yeast homolog, BRSK1 is thought to be involved in stress-induced cell cycle arrest. Overexpression of this protein leads to the G2/M arrest in HeLa S2 cells and UV-induced G2/M arrest could be partially abrogated by reduced expression of BRSK1 through the use of siRNA, indicating its role in DNA damage checkpoint function.



Images

01rOF7GDKbvKKyO.jpg

 WB analysis of BRSK1(GB111548).
Sample: Protein treated by RIPA Lysis Buffer (G2002).
Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h.
Primary antibody: 1: 500, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.



Storage


Storage Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.


: AO-03-GB111548-100
: 10 Produits
Hurry! only 10 items left in stock.

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