Anti-TSG101 Rabbit pAb (N-terminal)

Anti-TSG101 Rabbit pAb (N-terminal)

Antibodies Oncology
AO-03-GB11618-100
TSG101,TSG-101,外泌体标记物,GB11618,GB11618100,VPS23,外泌体marker,tumor susceptibility 101,TSG 101,TSG10,外泌体标志物,外泌体,TSG101(N-terminal),11618,Tumor susceptibility gene 101 protein,tumor susceptibility gene 101,Cell and organelle markers,ESCRT I complex subunit TSG101,Exosome marker
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Product Information


Protein full name

Tumor susceptibility gene 101 protein

Synonyms

TSG10, TSG101, tumor susceptibility gene 101, VPS23, tumor susceptibility 101, Cell and organelle markers, ESCRT I complex subunit TSG101, Exosome marker

Uniprot ID

Q61187

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse TSG101(N-terminal)

Isotype

IgG

Predicted MW./Observed MW.

44 kDa / 46 kDa

Purity

Affinity purification

Subcellular location

Cytoplasm, Early endosome membrane, Late endosome membrane, Nucleus



Applications


Applications Species Dilution Positive Tissue
WB Human, Mouse, Rat 1: 500-1: 1000 liver, lung, brain
ICC/IF Mouse 1: 50-1: 200 NIH-3T3



Background

Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity).



Images

011Z5FzgaIhM1er.jpg

 WB analysis of TSG101 (N-terminal)(GB11618).
Sample: Protein treated by RIPA Lysis Buffer (G2002).
Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h.
Primary antibody: 1: 500, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.

02Jfo4yjsqAAb4w.jpg

 ICC analysis of TSG101 (N-terminal)(GB11618)red.
Sample: NIH-3T3, 4% PFA (G1101) 20min.
Blocking buffer: 3% BSA (GC305010) in PBS, RT, 30min.
Primary antibody: 1: 50, 4℃ overnight.
Secondary antibody: Cy3 conjugated Goat Anti-Rabbit IgG (H+L) (GB21303), 1: 300, RT, 1h.



Storage


Storage Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.


: AO-03-GB11618-100
: 10 Produits
Hurry! only 10 items left in stock.

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