Recombinant Anti-Bax antibody (Rabbit mAb)
   

Recombinant Anti-Bax antibody (Rabbit mAb)

Antibodies Oncology
AO-03-GB154122-100
154122,BCL2L4,GB154122,BAX,BCL2 associated X protein,Apoptosis regulator BAX,BCL2 associated X,Bcl2-L-4,Bax-protein,Bcl-2-Like Protein 4,Apoptosis regulator BAX,GB11007
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Product Information


Protein full name

Apoptosis regulator BAX

Synonyms

BAX, BCL2L4, BCL2 associated X protein, BCL2 associated X, Apoptosis regulator BAX, Bcl-2-Like Protein 4,Bcl2-L-4, Bax-protein, apoptosis regulator

Uniprot ID

Q07812

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Bax

Isotype

IgG, κ

Clone Number

SB130

Purity

Affinity purification

Subcellular location

Mitochondrion, Cytoplasm



Applications


Applications Species Dilution Positive Tissue
IHC/IF Human, Mouse, Rat 1: 500-1: 1000 colon cancer,esophageal carcinoma, kidney



Background

Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.



Images

016IPFcE2bFzaPR.jpg

 IHC analysis of Bax(GB154122).
Sample: Human colon cancer, 4% PFA (G1101) 12-24h.
Antigen retrieval: Citrate buffer (pH 6.0) (G1201), pressure cooker 2 min.
Primary antibody: 1: 500, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.

02RX65RdbuINqAQ.jpg

 IHC analysis of Bax(GB154122).
Sample: Human esophageal carcinoma, 4% PFA (G1101) 12-24h.
Antigen retrieval: Citrate buffer (pH 6.0) (G1201), pressure cooker 2 min.
Primary antibody: 1: 500, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.

03mS2igxCRxiTd0.jpg

 IHC analysis of Bax(GB154122).
Sample: Mouse kidney, 4% PFA (G1101) 12-24h.
Antigen retrieval: Citrate buffer (pH 6.0) (G1201), pressure cooker 2 min.
Primary antibody: 1: 500, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.

0432ZHBcu1hh4Rz.jpg

 IHC analysis of Bax(GB154122).
Sample: Mouse liver, 4% PFA (G1101) 12-24h.
Antigen retrieval: Citrate buffer (pH 6.0) (G1201), pressure cooker 2 min.
Primary antibody: 1: 500, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.

05aQdPJl3fA8Lpj.jpg

 IHC analysis of Bax(GB154122).
Sample: Rat kidney, 4% PFA (G1101) 12-24h.
Antigen retrieval: Citrate buffer (pH 6.0) (G1201), pressure cooker 2 min.
Primary antibody: 1: 500, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.

065fJFYhQD7SWmr.jpg

 IHC analysis of Bax(GB154122).
Sample: Rat liver, 4% PFA (G1101) 12-24h.
Antigen retrieval: Citrate buffer (pH 6.0) (G1201), pressure cooker 2 min.
Primary antibody: 1: 500, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.



Storage


Storage Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.


: AO-03-GB154122-100
: 10 Produits
Hurry! only 10 items left in stock.

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