Anti-Smac/Diablo Rabbit pAb

Anti-Smac/Diablo Rabbit pAb

Antibodies Oncology
AO-03-GB115506-50
DIABLO S,Diablo homolog,diablo homolog (Drosophila),GB115506,SMAC3,mitochondrial,SMAC,Smac,DIABLO,Diablo,SmacDiablo,115506,Smac Diablo,Diablo homolog,mitochondrial
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Product Information


Protein full name

Diablo homolog, mitochondrial

Synonyms

Diablo, DIABLO, DFNA64, SMAC, Diablo, Diablo homolog, diablo IAP-binding mitochondrial protein, Smac, diablo homolog (Drosophila),mitochondrial, DIABLO S, SMAC3

Uniprot ID

Q9JIQ3

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Smac

Isotype

IgG

Purity

Affinity purification

Subcellular location

Mitochondrion



Applications


Applications Species Dilution Positive Tissue
IHC/IF Mouse 1: 200-1: 400 testis



Background

Diablo homolog (DIABLO) is a mitochondrial protein encoded by the DIABLO gene. SMAC is a mitochondrial protein that promotes cytochrome c- and TNF receptor-dependent activation of apoptosis by inhibiting the effect of IAP–a protein that negatively regulates apoptosis, or programmed cell death. SMAC is normally a mitochondrial protein localized to the mitochondrial intermembrane space, but it enters the cytosol when cells undergo apoptosis.



Images

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 IHC analysis of Smac/Diablo(GB115506).
Sample: Mouse testis, 4% PFA (G1101) 12-24h.
Antigen retrieval: Tris-EDTA buffer (pH 9.0) (G1203), 98℃, 20min.
Primary antibody: 1: 200, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.



Storage


Storage Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.


: AO-03-GB115506-50
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Hurry! only 10 items left in stock.

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