Anti-Caspase-12 Rabbit pAb

AO-03-GB111695-100
Anti- Caspase-12 Rabbit pAb,Caspase 12,CASP-12,GB111695,CASP12P1,GB111695100,caspase 12 pseudogene 1,nactive caspase-12,111695,Casp12,Caspase12,Caspase-12,casepase,Caspase-12,capase
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Product Information


Protein full name

Caspase-12

Synonyms

Casp12, CASP-12, CASP12P1, Inactive caspase-12, caspase 12 pseudogene 1, caspase 12 (gene/pseudogene)

Uniprot ID

O08736

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Caspase-12

Isotype

IgG

Predicted MW./Observed MW.

48 kDa / 48 kDa

Purity

Affinity purification




Applications


Applications Species Dilution Positive Tissue
WB Human, Mouse, Rat 1: 500-1: 1000 testis, spleen, kidney




Background

Caspase 12 is an enzyme known as a cysteine protease. It belongs to a family of enzymes called caspases that cleave their substrates at C-terminal aspartic acid residues. It is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. Caspase-12 is located in the endoplasmic reticulum (ER). It is responsible for ER-stress-induced apoptosis, such as high calcium concentration, low oxygen and low glucose levels.




Images

01KM3q30t9mdJs6.jpg

WB analysis of Caspase-12(GB111695).
Sample: Protein treated by RIPA Lysis Buffer (G2002).
Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h.
Primary antibody: 1: 500, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.

025cBVMYoRR0fGX.jpg

WB analysis of Caspase-12(GB111695).
Sample: Protein treated by RIPA Lysis Buffer (G2002).
Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h.
Primary antibody: 1: 500, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.




Storage


Storage Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).


: AO-03-GB111695-100
: 10 Produits
Hurry! only 10 items left in stock.

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