Anti-Bax Mouse mAb

Anti-Bax Mouse mAb

Antibodies Oncology
AO-03-GB12690-100
12690,GB12690100,BCL2L4,Bax,BAX,BCL2 associated X protein,BCL2 associated X,GB12690,apoptosis regulator,Apoptosis regulator BAX,GB11007
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Product Information


Protein full name

Apoptosis regulator BAX

Synonyms

BAX, BCL2L4, BCL2 associated X protein, BCL2 associated X, Apoptosis regulator BAX, Bcl-2-Like Protein 4,Bcl2-L-4, Bax-protein, apoptosis regulator

Uniprot ID

Q07813

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Bax

Isotype

IgG1, κ

Clone Number

6D12C9

Predicted MW./Observed MW.

21 kDa / 21 kDa

Purity

Affinity purification



Applications


Applications Species Dilution Positive Tissue
WB Human, Mouse, Rat 1: 500-1: 1000 liver, lung, kidney



Background

Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.



Images

01HXK1WbktT2vCn.jpg

 WB analysis of Bax(GB12690).
Sample: Protein treated by RIPA Lysis Buffer (G2002).
Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h.
Primary antibody: 1: 1000, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Mouse lgG (H+L) (GB23301), 1: 5000, RT, 1h.

02nwY6JMgyW94tg.jpg

 WB analysis of Bax(GB12690).
Sample: Protein treated by RIPA Lysis Buffer (G2002).
Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h.
Primary antibody: 1: 1000, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Mouse lgG (H+L) (GB23301), 1: 5000, RT, 1h.



Storage


Storage Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.


: AO-03-GB12690-100
: 10 Produits
Hurry! only 10 items left in stock.

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