Anti-Caspase-12 Mouse mAb

Anti-Caspase-12 Mouse mAb

Antibodies Oncology
AO-03-GB12548-100
Caspase 12,CASP-12,12548,GB12548100,CASP12P1,caspase 12 pseudogene 1,caspase 12 (gene/pseudogene),Inactive caspase-12,GB12548,Casp12,Caspase12,Caspase-12,casepase,Caspase-12,capase
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Product Information


Protein full name

Caspase-12

Synonyms

Casp12, CASP-12, CASP12P1, Inactive caspase-12, caspase 12 pseudogene 1, caspase 12 (gene/pseudogene)

Uniprot ID

O08736

Immunogen

Recombinant protein corresponding to Mouse Caspase-12

Isotype

IgG1, κ

Clone Number

3A3D1

Predicted MW./Observed MW.

48 kDa / 48 kDa

Purity

Affinity purification



Applications


Applications Species Dilution Positive Tissue
WB Mouse 1: 500-1: 1000 skin, stomach



Background

Caspase 12 is an enzyme known as a cysteine protease. It belongs to a family of enzymes called caspases that cleave their substrates at C-terminal aspartic acid residues. It is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. Caspase-12 is located in the endoplasmic reticulum (ER). It is responsible for ER-stress-induced apoptosis, such as high calcium concentration, low oxygen and low glucose levels.



Images

01tVpzcz5PNOoOf.jpg

 WB analysis of Caspase-12(GB12548).
Sample: Protein treated by RIPA Lysis Buffer (G2002).
Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h.
Primary antibody: 1: 1000, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Mouse lgG (H+L) (GB23301), 1: 5000, RT, 1h.

02dz6mjORFxJrUI.jpg

 WB analysis of Caspase-12(GB12548).
Sample: Protein treated by RIPA Lysis Buffer (G2002).
Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h.
Primary antibody: 1: 1000, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Mouse lgG (H+L) (GB23301), 1: 5000, RT, 1h.



Storage


Storage Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.


: AO-03-GB12548-100
: 10 Produits
Hurry! only 10 items left in stock.

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