Anti-Caspase-9 Rabbit pAb

Anti-Caspase-9 Rabbit pAb

Antibodies Oncology
AO-03-GB11053-1-100
ASP9,caspase9,GB110531100,caspase-9,11053-1,APAF-3,GB11053-1,Caspase-9,Caspase 9,GB110531,ICE-LAP6,GB11053 1,MCH6,caspase 9,Caspase9,APAF3,PPP1R56,casepase,Caspase-9,capase,caspase9,caspase 9
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Product Information


Protein full name

Caspase-9

Synonyms

CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56, caspase 9

Uniprot ID

Q8C3Q9

Immunogen

Recombinant protein corresponding to Mouse Caspase-9

Isotype

IgG

Predicted MW./Observed MW.

50 kDa (M) 51 kDa (R) / 50/37 kDa (M) 51/38 kDa (R)

Purity

Affinity purification



Applications


Applications Species Dilution Positive Tissue
WB Mouse, Rat 1: 800-1: 1000 heart, brain, skeletal muscle



Background

Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 35 kDa (p35) and a 10 kDa (p10) subunit. Caspase-9 and APAF1 bind to each other via their respective NH2-terminal CED-3 homologous domains in the presence of cytochrome C and ATP. Interacts (inactive form) with EFHD2. Interacts with HAX1. Interacts with BIRC2/c-IAP1, XIAP/BIRC4, BIRC5/survivin, BIRC6/bruce and BIRC7/livin. Interacts with ABL1 (via SH3 domain); the interaction is direct and increased in the response of cells to genotoxic stress and ABL1/c-Abl activation.



Images

01EslXA380ZaGgb.jpg

 WB analysis of Caspase-9(GB11053-1).
Sample: Protein treated by RIPA Lysis Buffer (G2002).
Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h.
Primary antibody: 1: 800, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h.



Storage


Storage Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.


: AO-03-GB11053-1-100
: 10 Produits
Hurry! only 10 items left in stock.

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