Anti-MCL1 Rabbit pAb

Anti-MCL1 Rabbit pAb

Antibodies Oncology
AO-03-GB11696-100
GB11696100,MCL1L,Anti-MCL1 Rabbit pAb,MCL1,BCL2L3,GB11696,Mcl1,TM,MCL-1,MCL1S,Myeloid cell leukemia 1,BCL2 family apoptosis regulator,Mcl-1,EAT,bcl2-L-3,mcl1/EAT,MCL 1,11696,MCL1-ES,Induced myeloid leukemia cell differentiation protein Mcl-1 homolog
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Product Information


Protein full name

Induced myeloid leukemia cell differentiation protein Mcl-1 homolog

Synonyms

Mcl1, MCL1, BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT, Myeloid cell leukemia 1, BCL2 family apoptosis regulator, BCL2 family apoptosis regulator

Uniprot ID

Q07820

Immunogen

Recombinant protein corresponding to Human MCL1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus



Applications


Applications Species Dilution Positive Tissue
IHC/IF Human 1: 250-1: 1500 colon



Background

Induced myeloid leukemia cell differentiation protein Mcl-1 belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing.



Images

01zkp9igrpuiVL5.jpg

 IHC analysis of MCL1(GB11696).
Sample: Human colon, 4% PFA (G1101) 12-24h.
Antigen retrieval: Citrate buffer (pH 6.0) (G1201), 98℃, 20 min.
Primary antibody: 1: 250, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.

02YhqWstZoX2sAJ.jpg

 IHC analysis of MCL1(GB11696).
Sample: Human colon, 4% PFA (G1101) 12-24h.
Antigen retrieval: Citrate buffer (pH 6.0) (G1201), 98℃, 20 min.
Primary antibody: 1: 250, 4℃ overnight.
Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 200, RT, 1h.



Storage


Storage Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.


: AO-03-GB11696-100
: 10 Produits
Hurry! only 10 items left in stock.

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