Product Information
|
Protein full name |
Apoptotic chromatin condensation inducer in the nucleus |
|
Synonyms |
Acin1, ACIN1, ACINUS, ACN, fSAP152, apoptotic chromatin condensation inducer 1 |
|
Uniprot ID |
Q9JIX8 |
|
Immunogen |
Recombinant protein corresponding to Mouse Acinus |
|
Isotype |
IgG |
|
Predicted MW./Observed MW. |
151 kDa / 151 kDa |
|
Purity |
Affinity purification |
Applications
| Applications | Species | Dilution | Positive Tissue |
| WB | Human | 1: 500-1: 1000 | Jurkat, K562, HeLa |
Background
Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Induces apoptotic chromatin condensation after activation by CASP3.
Images
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WB analysis of Acinus(GB11786). Sample: Protein treated by RIPA Lysis Buffer (G2002). Blocking buffer: 3% Nonfat dry milk (GC310001) in TBST, RT, 1h. Primary antibody: 1: 500, 4℃ overnight. Secondary antibody: HRP conjugated Goat Anti-Rabbit lgG (H+L) (GB23303), 1: 5000, RT, 1h. |
Storage
| Storage | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.15% ProClin300, 100 μg/mL BSA and 50% glycerol. |
NOTE:
1.This product is intended for research only.
2.This product is recommended to dilute with the Primary Antibody Dilution Buffer （G2025）.
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