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Antibody Product Overview
| ELK.No | EA041 |
| Product name | Lamin B1 Rabbit pAb |
| Reactivity | Human, Rat, Mouse |
| Applications | WB, IHC |
| Other name | ADLD, LMB1,LMNB1, MGC111419, OTTHUMP00000159218 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 4001 |
| Human Swiss-Prot | P20700 |
| Source | Rabbit |
| Isotype | IgG |
| Target | |
| Fields | |
| Gene name | |
| Protein name | |
| Human gene link | |
| Human Swiss link | |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Recombinant Protein |
| Specificity | |
| Formulation | |
| Clonality | Polyclonal |
| Dilution | WB 1:1,000-3,000 IHC: 1:500-1,000 |
| Purification | |
| Concentration | 1mg/mL |
| Storage stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Molecular Weight (Da) | |
| Observed band (KD) | 68,45kDa |
| Background | The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. |
| Function | |
| Subcellular location | Mitochondrion inner membrane |
| Expression |
Additional Images
Western blot analysis of 1) 293T, 2)Mouse Brain, 3) Rat Brain tissue with EA041 diluted at 1:2,000.
Immunohistochemical analysis of paraffin-embedded Mouse Kidney Tissue using Lamin B1 (EA041) Rabbit pAb diluted at 1:500.
: AO-06-EA041-50
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