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Antibody Product Overview
| ELK.No | EA219 |
| Product name | MEK1 Rabbit pAb |
| Reactivity | Human, Rat, Mouse |
| Applications | WB, IHC |
| Other name | ERK activator kinase 1 antibody, MAPK kinase kinase 1 antibody, MEKK1 antibody, MKK1 antibody, PRKMK 1 antibody |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 5604 |
| Human Swiss-Prot | Q02750 |
| Source | Rabbit |
| Isotype | IgG |
| Target | |
| Fields | |
| Gene name | |
| Protein name | |
| Human gene link | |
| Human Swiss link | |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Recombinant Protein |
| Specificity | |
| Formulation | |
| Clonality | Polyclonal |
| Dilution | WB 1:1,000-2,000 IHC 1:100-200 |
| Purification | |
| Concentration | 1mg/mL |
| Storage stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Molecular Weight (Da) | |
| Observed band (KD) | 45kDa |
| Background | MEK1 and MEK2, also called MAPK or Erk kinases, are dual-specificity protein kinases that function in a mitogen activated protein kinase cascade controlling cell growth and differentiation. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases. |
| Function | |
| Subcellular location | |
| Expression |
Additional Images
Western blot analysis of 1) Hela, 2)3T3, 3)PC12 with MEK1 Rabbit pAb EA219 diluted at 1:2,000.
Immunohistochemical analysis of paraffin-embedded Human Colon Carcinoma using MEK1 （EA219）Rabbit pAb diluted at 1:200.
Western blot analysis of extracts from MG63 (Lane 1),MCF-7 (Lane 2), 3T3 (Lane 3), Rat Kidney (Lane 4), using MEK1 diluted at 1:50,000.
: AO-06-EA219-50
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