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Antibody Product Overview
| ELK.No | EA363 |
| Product name | Bmi-1 (F270)Rabbit pAb |
| Reactivity | Human |
| Applications | WB |
| Other name | PCGF4, Polycomb complex protein BMI 1, RING finger protein 51, RNF51 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 100532731 |
| Human Swiss-Prot | P35226 |
| Source | Rabbit |
| Isotype | IgG |
| Target | |
| Fields | |
| Gene name | |
| Protein name | |
| Human gene link | |
| Human Swiss link | |
| Mouse gene ID | |
| Mouse gene link | |
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| Mouse Swiss link | |
| Rat gene ID | |
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| Rat Swiss link | |
| Immunogen | Recombinant Protein |
| Specificity | |
| Formulation | |
| Clonality | Polyclonal |
| Dilution | WB 1:1,000-2,000 |
| Purification | |
| Concentration | 1mg/mL |
| Storage stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Molecular Weight (Da) | |
| Observed band (KD) | 37-43kDa |
| Background | Bmi1 is a component of the PRC1 complex, which together with Ring1 strongly enhances the E3 ubiquitin ligase activity of the Ring2 catalytic subunit . Bmi1 plays an important role in the regulation of cell proliferation and senescence through repression of the p16 INK4A and p19 ARF genes and is required for maintenance of adult hematopoietic and neural stem cells . |
| Function | |
| Subcellular location | Cytoplasm, Nucleus |
| Expression |
Additional Images
Western blot analysis of Hela Cell Lysate using Bmi-1（EA363）Rabbit pAb diluted at 1:2000.
: AO-06-EA363-100
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