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Antibody Product Overview
| ELK.No | EA366 |
| Product name | Calreticulin Rabbit pAb |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Other name | CALR, Calregulin, cC1qR, CRP55, CRT, CRTC, ERp60, grp60, HACBP, RO, SSA |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 811 |
| Human Swiss-Prot | P27797 |
| Source | Rabbit |
| Isotype | IgG |
| Target | |
| Fields | |
| Gene name | |
| Protein name | |
| Human gene link | |
| Human Swiss link | |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Recombinant Protein |
| Specificity | |
| Formulation | |
| Clonality | Polyclonal |
| Dilution | WB 1:500-1,000 |
| Purification | |
| Concentration | 1mg/mL |
| Storage stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Molecular Weight (Da) | |
| Observed band (KD) | 55kDa |
| Background | Calcium is a universal signaling molecule involved in many cellular functions such as cell motility, metabolism, protein modification, protein folding, and apoptosis. Calcium is stored in the endoplasmic reticulum (ER), where it is buffered by calcium binding chaperones such as calnexin and calreticulin, and is released via the IP3 Receptor channel . Calreticulin also functions as an ER chaperone that ensures proper folding and quality control of newly synthesized glycoproteins. As such, calreticulin presumably does not alter protein folding but regulates proper timing for efficient folding and subunit assembly. Furthermore, calreticulin retains proteins in non-native conformation within the ER and targets them for degradation . |
| Function | |
| Subcellular location | Cytoplasm, Endoplasmic reticulum, Extracellular matrix, Sarcoplasmic reticulum, Secreted |
| Expression |
Additional Images
Western blot analysis of 1) Rat Skeletal Muscle Tissue Lysate, 2) Hela Cell Lysate , 3) 3T3 Cell Lysate using Calreticulin（EA366）Rabbit pAb diluted at 1:1000.
: AO-06-EA366-50
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