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Antibody Product Overview
| ELK.No | ES10010 |
| Product name | PAIRB rabbit pAb |
| Reactivity | Human;Rat;Mouse |
| Applications | WB;ELISA |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 26135 |
| Human Swiss-Prot | Q8NC51 |
| Source | Rabbit |
| Isotype | IgG |
| Target | PAIRB |
| Fields | |
| Gene name | SERBP1 PAIRBP1 CGI-55 |
| Protein name | Plasminogen activator inhibitor 1 RNA-binding protein (PAI1 RNA-binding protein 1) (PAI-RBP1) (SERPINE1 mRNA-binding protein 1) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q9CY58 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | Q6AXS5 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 60-140 |
| Specificity | PAIRB Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 44kD |
| Background | function:May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay.,subcellular location:Also found in perinuclear regions.,subunit:Interacts with CHD3 and TDRD3.,tissue specificity:Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain., |
| Function | function:May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay.,subcellular location:Also found in perinuclear regions.,subunit:Interacts with CHD3 and TDRD3.,tissue specificity:Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain., |
| Subcellular location | Cytoplasm . Nucleus . Cytoplasm, perinuclear region . |
| Expression | Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain. |
Additional Images
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Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES10010-50
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