KCNE4 rabbit pAb

KCNE4 rabbit pAb

AO-06-ES10029-100

KCNE4 rabbit pAb 100μL

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Antibody Product Overview

ELK.NoES10029
Product nameKCNE4 rabbit pAb
ReactivityHuman;Mouse
ApplicationsWB;ELISA
Other name
Size100μL
Unit price ($)248
Human gene ID23704
Human Swiss-ProtQ8WWG9
SourceRabbit
IsotypeIgG
TargetKCNE4
Fields
Gene nameKCNE4
Protein namePotassium voltage-gated channel subfamily E member 4 (MinK-related peptide 3) (Minimum potassium ion channel-related peptide 3) (Potassium channel subunit beta MiRP3)
Human gene link
Human Swiss linkView Human Swiss-Prot
Mouse gene ID
Mouse gene link
Mouse Swiss-ProtQ9WTW3
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID
Rat gene link
Rat Swiss-Prot
Rat Swiss link
ImmunogenSynthesized peptide derived from human protein . at AA range: 90-170
SpecificityKCNE4 Polyclonal Antibody detects endogenous levels of protein.
FormulationLiquid in PBS containing 50% glycerol, and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWB 1:500-2000 ELISA 1:5000-20000
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)
Observed band (KD)18kD
Backgroundpotassium voltage-gated channel subfamily E regulatory subunit 4(KCNE4) Homo sapiens Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the embryo and in adult uterus. [provided by RefSeq, Jul 2008],
Functionfunction:Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex.,function:Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. May associate with KCNQ1/KVLTQ1 and inhibit potassium current.,similarity:Belongs to the potassium channel KCNE family.,subunit:Associates with KCNQ1/KVLQT1.,tissue specificity:Predominantly expressed in embryo and adult uterus. Low expression found in kidney, small intestine, lung and heart.,
Subcellular locationMembrane ; Single-pass membrane protein .
ExpressionPredominantly expressed in embryo and adult uterus. Low expression found in kidney, small intestine, lung and heart.

Additional Images

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Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES10029-100
: 10 Produits
Hurry! only 10 items left in stock.

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