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Antibody Product Overview
| ELK.No | ES10061 |
| Product name | PPME1 rabbit pAb |
| Reactivity | Human;Rat;Mouse |
| Applications | WB;ELISA |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 51400 |
| Human Swiss-Prot | Q9Y570 |
| Source | Rabbit |
| Isotype | IgG |
| Target | PPME1 |
| Fields | |
| Gene name | PPME1 PME1 PP2593 PRO0750 |
| Protein name | Protein phosphatase methylesterase 1 (PME-1) (EC 3.1.1.89) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q8BVQ5 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | Q4FZT2 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 220-300 |
| Specificity | PPME1 Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 42kD |
| Background | This gene encodes a protein phosphatase methylesterase localized to the nucleus. The encoded protein acts on the protein phosphatase-2A catalytic subunit and supports the ERK pathway through dephosphorylation of regulatory proteins. It plays a role in malignant glioma progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012], |
| Function | function:Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro).,sequence caution:Wrong choice of CDS.,similarity:Belongs to the AB hydrolase superfamily.,subunit:Binds PPP2CB., |
| Subcellular location | cell-cell adherens junction, |
| Expression | Amygdala,Cervix carcinoma,Fetal liver,Lung,Platelet,Skin, |
Additional Images
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Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES10061-50
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