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Antibody Product Overview
| ELK.No | ES10118 |
| Product name | RAB23 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 51715 |
| Human Swiss-Prot | Q9ULC3 |
| Source | Rabbit |
| Isotype | IgG |
| Target | RAB23 |
| Fields | |
| Gene name | RAB23 HSPC137 |
| Protein name | Ras-related protein Rab-23 |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | P35288 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 120-200 |
| Specificity | RAB23 Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 26kD |
| Background | This gene encodes a small GTPase of the Ras superfamily. Rab proteins are involved in the regulation of diverse cellular functions associated with intracellular membrane trafficking, including autophagy and immune response to bacterial infection. The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling. Disruption of this gene has been implicated in Carpenter syndrome as well as cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013], |
| Function | disease:Defects in RAB23 are the cause of Carpenter syndrome [MIM:201000]; also known as acrocephalopolysyndactyly type 2 (ACPS2). Carpenter syndrome is characterized by craniosynostosis, polysyndactyly, obesity, and cardiac defects. Inheritance is autosomal recessive.,similarity:Belongs to the small GTPase superfamily. Rab family., |
| Subcellular location | Cell membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasm . Cytoplasmic vesicle, autophagosome . Endosome membrane . Cytoplasmic vesicle, phagosome . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Recruited to phagosomes containing S.aureus or M.tuberculosis. . |
| Expression | Brain,Fetal brain,Hair follicle,Umbilical cord blood,Uterus, |
Additional Images
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Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES10118-50
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